{"id":991528,"date":"2026-09-30T10:52:49","date_gmt":"2026-09-30T08:52:49","guid":{"rendered":"https:\/\/slift.hr\/?post_type=stanja_koze&#038;p=991528"},"modified":"2026-10-06T09:16:00","modified_gmt":"2026-10-06T07:16:00","slug":"melazma","status":"publish","type":"stanja_koze","link":"https:\/\/slift.hr\/en\/stanja-koze\/melazma\/","title":{"rendered":"Melazma"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"991528\" class=\"elementor elementor-991528\" data-elementor-post-type=\"stanja_koze\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c6615ea e-flex e-con-boxed e-con e-parent\" data-id=\"c6615ea\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"vamtam-has-theme-widget-styles elementor-element elementor-element-8762f2e elementor-widget elementor-widget-text-editor\" data-id=\"8762f2e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><b>Description:<\/b><span style=\"font-weight: 400;\"> Melasma manifests as symmetrical, dark brown patches with irregular borders on the face (cheeks, forehead, upper lip). Post-inflammatory hyperpigmentation (PIH) consists of dark spots that remain on the face or body after an inflammatory process (acne, eczema, burns, or aggressive aesthetic treatments) has resolved; it is more common in darker Fitzpatrick skin phototypes.<\/span><\/p><p><b>Causes:<\/b><span style=\"font-weight: 400;\"> Melasma is triggered by a combination of UV radiation and hormonal stimuli (pregnancy, contraceptives, estrogen) that prompt melanocytes to produce excess pigment. PIH occurs because inflammatory mediators (cytokines) directly stimulate melanocytes to increase pigment synthesis and transfer pigment to surrounding skin cells at the site of injury.<\/span><\/p><p><b>Best management strategies:<\/b><\/p><p><b>Effective sun protection:<\/b><span style=\"font-weight: 400;\"> Daily application of a broad-spectrum sunscreen with a high SPF (30 or higher), ideally containing physical filters (zinc oxide and titanium dioxide).<\/span><\/p><p><b>Gold standard (triple combination formula):<\/b><span style=\"font-weight: 400;\"> Short-term (intermittent) protocols using a cream that combines hydroquinone 4% (blocks the enzyme tyrosinase), tretinoin 0.05% (accelerates cell turnover and pigment shedding), and a mild corticosteroid, fluocinolone acetonide 0.01% (calms melanocytes). Avoid long-term use of hydroquinone alone because it can cause exogenous ochronosis. Economical and long-term alternatives: Tranexamic acid (TXA) \u2013 oral or topical, azelaic acid, kojic acid, niacinamide (blocks the transfer of pigment to keratinocytes) and tazarotene 0.045% in polymer emulsion for excellent tolerability.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9f742ca e-flex e-con-boxed e-con e-parent\" data-id=\"9f742ca\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3bc2fd4 e-con-full e-flex e-con e-child\" data-id=\"3bc2fd4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-557fe19 e-con-full e-flex e-con e-child\" data-id=\"557fe19\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-fce3721 e-con-full e-flex e-con e-child\" data-id=\"fce3721\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-71b9a82 animated-fast elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"71b9a82\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Important note: <\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"vamtam-has-theme-widget-styles elementor-element elementor-element-8cc1ff5 animated-fast elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"8cc1ff5\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;,&quot;_animation_delay&quot;:100}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The information presented in this text is of a general nature and cannot replace a professional dermatological examination. The content published on S Lift serves exclusively for educational and informative purposes and does not represent medical advice, diagnosis or treatment recommendations. Since every skin reacts uniquely, we recommend a professional diagnosis before introducing new active ingredients, routines, or treatments. To diagnose dermatological diseases, you must consult a doctor or dermatologist. S Lift maintains its focus on holistic care and advanced cosmetology. For an advanced View Skin analysis, visit the S Lift boutique beauty salon at Ka\u010di\u0107eva 10 in Zagreb for a personalised approach and consultation tailored to your digital skin impression.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Opis: Melazma se o\u010dituje u obliku simetri\u010dnih, tamnosme\u0111ih mrlja nepravilnih rubova na licu (obrazi, \u010delo, gornja usna). Postupalna hiperpigmentacija (PIH) predstavlja tamne mrlje koje zaostaju na ko\u017ei lica ili tijela nakon \u0161to pro\u0111e upalni proces (akne, ekcem, opekline ili agresivni estetski tretmani), a \u010de\u0161\u0107a je kod tamnijih fototipova ko\u017ee po Fitzpatricku. Uzroci nastanka: Melazmu pokre\u0107e&#8230;<\/p>","protected":false},"featured_media":992068,"template":"","meta":{"googlesitekit_rrm_CAowkOHLDA:productID":""},"kategorija_stanja_koze":[76],"class_list":["post-991528","stanja_koze","type-stanja_koze","status-publish","has-post-thumbnail","hentry","kategorija_stanja_koze-pigmentacijski-poremecaji-koze"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Melazma - S Lift<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/slift.hr\/en\/stanja-koze\/melazma\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Melazma - S Lift\" \/>\n<meta property=\"og:description\" content=\"Opis: Melazma se o\u010dituje u obliku simetri\u010dnih, tamnosme\u0111ih mrlja nepravilnih rubova na licu (obrazi, \u010delo, gornja usna). Postupalna hiperpigmentacija (PIH) predstavlja tamne mrlje koje zaostaju na ko\u017ei lica ili tijela nakon \u0161to pro\u0111e upalni proces (akne, ekcem, opekline ili agresivni estetski tretmani), a \u010de\u0161\u0107a je kod tamnijih fototipova ko\u017ee po Fitzpatricku. 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