Facial vascular hyperreactivity manifesting as transient or persistent redness (flushing), caused by dysfunction of the innate immune system and neurovascular regulation.
Description: A chronic inflammatory and neurovascular disease affecting the face (forehead, nose, cheeks, chin) exclusively. It is characterised by episodes of redness and heat (flushing), persistent redness (erythema), dilated capillaries (telangiectasias), inflammatory lesions (papulopustular rosacea), and, in later stages, tissue thickening (phymatous changes, e.g., rhinophyma).
Causes: It arises from innate immune hypersensitivity (activation of TLR-2 receptors and excessive production of the pro-inflammatory cathelicidin LL-37) and neurovascular sensitivity (TRPV1 channels on nerves overreact and release neuropeptides that dilate blood vessels and promote inflammation). Excessive concentrations of Demodex mites in the follicles are also common. Key triggers include UV radiation, stress, temperature changes, alcohol (especially red wine), spicy food, and foods rich in histamine (tomatoes, chocolate, citrus fruits).
Best management strategies:
Protection and care: Strictly avoid triggers, cleanse only with gentle products, and use daily protection with mineral UV filters (zinc oxide and titanium dioxide, which do not generate heat on the skin).
Topical treatments: Ivermectin 1% cream (which eliminates Demodex and reduces inflammation), azelaic acid, metronidazole, or microencapsulated benzoyl peroxide are used for pimples. Topical vasoconstrictors (brimonidine, oxymetazoline) are used to reduce redness.
Important note:
The information presented in this text is of a general nature and cannot replace a professional dermatological examination. The content published on S Lift serves exclusively for educational and informative purposes and does not represent medical advice, diagnosis or treatment recommendations. Since every skin reacts uniquely, we recommend a professional diagnosis before introducing new active ingredients, routines, or treatments. To diagnose dermatological diseases, you must consult a doctor or dermatologist. S Lift maintains its focus on holistic care and advanced cosmetology. For an advanced View Skin analysis, visit the S Lift boutique beauty salon at Kačićeva 10 in Zagreb for a personalised approach and consultation tailored to your digital skin impression.
